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John M Zajecka Selected Research

5-methyltetrahydrofolate

5/2016Long-term efficacy, safety, and tolerability of L-methylfolate calcium 15 mg as adjunctive therapy with selective serotonin reuptake inhibitors: a 12-month, open-label study following a placebo-controlled acute study.
12/2015Association of obesity and inflammatory marker levels on treatment outcome: results from a double-blind, randomized study of adjunctive L-methylfolate calcium in patients with MDD who are inadequate responders to SSRIs.
8/2014Effect of adjunctive L-methylfolate 15 mg among inadequate responders to SSRIs in depressed patients who were stratified by biomarker levels and genotype: results from a randomized clinical trial.
12/2012L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials.

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John M Zajecka Research Topics

Disease

12Major Depressive Disorder (Major Depressive Disorders)
01/2019 - 01/2004
3Mania (Manias)
06/2008 - 12/2002
3Bipolar Disorder (Manic Depressive Psychosis)
11/2006 - 12/2002
2Depressive Disorder (Melancholia)
08/2007 - 07/2007
1Substance Withdrawal Syndrome (Withdrawal Symptoms)
01/2019
1Treatment-Resistant Depressive Disorder
01/2017
1Obesity
12/2015
1Inflammation (Inflammations)
08/2014
1Fatigue
01/2009
1Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
01/2006
1Diabetic Ketoacidosis (Ketoacidosis, Diabetic)
12/2002
1Body Weight Changes
12/2002
1Sleepiness
12/2002
1Weight Gain
12/2002
1Rhinitis
12/2002
1Edema (Dropsy)
12/2002

Drug/Important Bio-Agent (IBA)

6Antidepressive Agents (Antidepressants)IBA
01/2019 - 01/2009
5Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric
11/2010 - 11/2006
45-methyltetrahydrofolateIBA
05/2016 - 12/2012
3Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
05/2016 - 12/2012
3Valproic Acid (Depakote)FDA LinkGeneric
06/2008 - 12/2002
2Fluoxetine (Prozac)FDA LinkGeneric
08/2007 - 07/2007
2Sertraline (Zoloft)FDA LinkGeneric
11/2006 - 01/2006
2Olanzapine (Zyprexa)FDA Link
03/2003 - 12/2002
1Opiate AlkaloidsIBA
01/2019
1Opioid Analgesics (Opioids)IBA
01/2019
1Buprenorphine (Subutex)FDA LinkGeneric
01/2019
13-carboxamido-4-hydroxynaltrexoneIBA
01/2019
1N-Methylaspartate (NMDA)IBA
03/2017
1AZD6765IBA
03/2017
1CalciumIBA
12/2015
1Biomarkers (Surrogate Marker)IBA
08/2014
1ziprasidone (Geodon)FDA Link
12/2012
1Serotonin and Noradrenaline Reuptake InhibitorsIBA
01/2004
1Antipsychotic Agents (Antipsychotics)IBA
03/2003

Therapy/Procedure

4Therapeutics
01/2019 - 11/2006
1Vagus Nerve Stimulation
01/2017